EV storage is a topic we are often asked about: Which buffers, what temperatures, and for how long? What is the impact on downstream applications of the EVs?
Health checks reduce downstream costs, both financial and medical. The same is true for cells, for which karyotyping is the fundamental test. Here we define the points where testing pays off, the interval to use in between, and the things that should send you to the cytogenetics laboratory whatever the passage count says.
Genetic audits are regularly carried out to determine the integrity of cells used in research. The utility of these audits depends on the question being asked.
Flux and pressure are process-critical parameters that change during tangential flow filtration (TFF). This article defines mechanisms, explains what rising pressure during a run actually tells you, and addresses the practical question of hollow fibre cartridge orientation.
