EVlution bench top TFF
Today we are launching the EVlution™ Tangential Flow Filtration (TFF) system designed to expand access to high-quality extracellular vesicle (EV) research. As EV science accelerates across academia, biotechnology, and clinical translation, scalable and reproducible purification technologies are becoming essential. TFF has emerged as one of the most powerful tools to meet this need.
Tangential flow filtartion (also know as cross-flow filtration), continuously flushes filtering surfaces with the sample to keep them clean.
In EV research, TFF enables efficient concentration, diafiltration, and buffer exchange while preserving vesicle integrity. Unlike traditional ultracentrifugation, which can be time-consuming, labor-intensive, and difficult to scale, EVlution™ TFF offers a gentle and continuous flow process that minimizes shear stress and aggregation. It allows researchers to process larger volumes, achieve higher recovery rates, and maintain better reproducibility across batches, an increasingly critical requirement for translational studies and therapeutic development.
EVlution™ TFF is particularly valuable in workflows involving conditioned media, biofluids, or large-scale cell culture systems. It supports removal of contaminants such as proteins, free nucleic acids, and small molecules while retaining vesicles within defined size ranges. For labs developing EV-based diagnostics, drug delivery systems, or regenerative medicine applications, EVlution™ TFF provides a pathway toward scalable and regulatory-aligned manufacturing processes.
Despite these advantages, many laboratories face barriers to adopting TFF technology. Conventional systems are often expensive, complex, and designed for industrial-scale bioprocessing rather than research environments. High capital costs, large footprints, and complicated setup requirements can limit access - particularly for academic labs, early-stage biotech startups, and research groups in emerging scientific communities.
EVlution™ provides an affordable bench top TFF system addresses this gap. By reducing cost, simplifying operation, and minimizing space requirements, EVlution enables access by all labs to this advanced purification technology. It empowers more labs to generate high-quality, reproducible EV preparations without relying on shared core facilities or outsourcing. This accessibility not only accelerates individual research programs but also strengthens the broader EV field by improving methodological consistency across studies.
The launch of EVlution™ platform represents more than a product introduction—it reflects a commitment to making scalable, high-performance EV purification available to all researchers. By lowering barriers to entry, we enable innovation, support translational progress, and help move extracellular vesicle science closer to clinical and commercial reality.
IMAGE EVlution TFF CREDIT CellGS
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